Jean-Christophe AVICE | Agricultural and Biological Sciences | Academic Citation Impact Award

Published on by Citation Awards

Jean-Christophe AVICE | Agricultural and Biological Sciences | Academic Citation Impact Award

UMR INRAe/Unicaen Plant Ecophysiology and Agronomy | France

Jean-Christophe Avice is a distinguished Professor of Plant Physiology at the University of Caen Normandie, where he also directs the Centre of Microscopy Applied to Biology (CMABio), the Master program in Biology and Agrosciences, and co-directs the regional Federation of Plant Science (Normandie Végétale). His scientific career spans advanced research in plant ecophysiology, with a focus on nutrient dynamics and metabolic interactions influencing crop performance and sustainability. Avice’s work has significantly contributed to understanding nitrogen (N) and sulfur (S) reserves in key species such as alfalfa, white clover, and oilseed rape, examining fluxes through isotopic tracing and characterizing vegetative storage proteins to elucidate their functions and regulatory mechanisms. He has also led research integrating diagnostic tool development, fluxomics using 15N and 34S tracers, proteomics, and molecular physiology to uncover the processes governing nutrient remobilization—particularly autophagy, transport mechanisms, and leaf senescence pathways that shape yield and seed quality. His studies extend to improving nutrient use efficiency and examining N–S–P interactions in major crops including oilseed rape, wheat, and soybean, offering insights into how nutrient balance influences oil content, protein accumulation, and micronutrient profiles. Through more than two decades of academic and research leadership, Avice has advanced scientific understanding of plant nutrition, stress physiology, and grain quality in oleoproteaginous and arable crops. His interdisciplinary approach bridges ecophysiology, agronomy, and molecular biology, supporting innovations in sustainable agriculture, crop management, and the development of biostimulants and diagnostic tools. As an educator and research director, he continues to contribute to scientific capacity-building and the advancement of plant science in the Normandie region and beyond.

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Featured Publications

  • Aranjuelo, I., Molero, G., Erice, G., Avice, J. C., & Nogués, S. (2011). Plant physiology and proteomics reveals the leaf response to drought in alfalfa (Medicago sativa L.). Journal of Experimental Botany, 62(1), 111–123.

  • Lee, B. R., Kim, K. Y., Jung, W. J., Avice, J. C., Ourry, A., & Kim, T. H. (2007). Peroxidases and lignification in relation to the intensity of water-deficit stress in white clover (Trifolium repens L.). Journal of Experimental Botany, 58(6), 1271–1279.

  • Guiboileau, A., Yoshimoto, K., Soulay, F., Bataillé, M. P., Avice, J. C., & Masclaux-Daubresse, C. (2012). Autophagy machinery controls nitrogen remobilization at the whole-plant level under both limiting and ample nitrate conditions in Arabidopsis. New Phytologist, 194(3), 732–740.

  • Abdallah, M., Dubousset, L., Meuriot, F., Etienne, P., Avice, J. C., & Ourry, A. (2010). Effect of mineral sulphur availability on nitrogen and sulphur uptake and remobilization during the vegetative growth of Brassica napus L. Journal of Experimental Botany, 61(10), 2635–2646.

  • Erice, G., Louahlia, S., Irigoyen, J. J., Sánchez-Díaz, M., & Avice, J. C. (2010). Biomass partitioning, morphology and water status of four alfalfa genotypes submitted to progressive drought and subsequent recovery. Journal of Plant Physiology, 167(2), 114–120.

  • Guiboileau, A., Yoshimoto, K., Soulay, F., Bataillé, M. P., Avice, J. C., & Masclaux-Daubresse, C. (2012). Autophagy machinery controls nitrogen remobilization at the whole-plant level under both limiting and ample nitrate conditions in Arabidopsis. New Phytologist, 194(3), 732–740.

  • Abdallah, M., Dubousset, L., Meuriot, F., Etienne, P., Avice, J. C., & Ourry, A. (2010). Effect of mineral sulphur availability on nitrogen and sulphur uptake and remobilization during the vegetative growth of Brassica napus L. Journal of Experimental Botany, 61(10), 2635–2646.

  • Erice, G., Irigoyen, J. J., Sánchez-Díaz, M., & Avice, J. C. (2007). Nitrogen and carbon flows estimated by ¹⁵N and ¹³C pulse-chase labeling during regrowth of alfalfa. Plant Physiology, 112(1), 281–290.

Anand Prakash Singh | Agricultural and Biological Sciences | Best Researcher Award

Published on by Citation Awards

Anand Prakash Singh | Agricultural and Biological Sciences | Best Researcher Award

University of Michigan | United States

Dr. Anand Prakash Singh is a Research Investigator at the Frankel Cardiovascular Center, Michigan Medicine, Ann Arbor, where he leads translational studies in cardio-oncology, cardio-immunology, heart failure with preserved ejection fraction (HFpEF), and exercise-induced cardiac regeneration. He earned his B.Sc. in Chemistry, Botany, and Zoology from the University of Lucknow (2007), M.Sc. in Biotechnology from the University of Allahabad, and Ph.D. in Molecular Medicine from Jawaharlal Nehru University, New Delhi. Following his doctorate, he completed postdoctoral training at prestigious institutions including South Asian University, Vanderbilt University Medical Center, the University of Alabama at Birmingham, and Massachusetts General Hospital/Harvard Medical School, while also serving as a visiting scholar at the Broad Institute of MIT and Harvard. His research focuses on understanding the molecular pathways of cardiac inflammation, senescence, and regeneration, particularly in the context of metabolic stress and cancer therapy–induced cardiotoxicity. Dr. Singh is the recipient of multiple competitive grants, including the Frankel Cardiovascular Center Inaugural Grant Award and VA IPA funding, and has contributed as Co-Investigator to major NIH and AHA projects exploring heart–brain interactions and exercise-mediated cardioprotection. Recognized for his scholarly excellence, he has received honors such as the First Prize for Oral Presentation at the International Conference on Innovation & Technologies in Medicine and Healthcare and the Outstanding Reviewer Award from Experimental Biology and Medicine. His ongoing research aims to bridge basic molecular mechanisms with clinical therapeutics for cardiovascular disease prevention and recovery.

Profile: Google Scholar

Featured Publications

Guo, H. L. Y., Gupte, M., Umbarkar, P., Singh, A. P., et al. (2017). Entanglement of GSK-3β, β-catenin and TGF-β1 signaling network to regulate myocardial fibrosis. Journal of Molecular and Cellular Cardiology, 174, Article 107–118.

Singh, A. P., Glennon, M. S., Umbarkar, P., Gupte, M., Galindo, C. L., Zhang, Q., et al. (2019). Ponatinib-induced cardiotoxicity: Delineating the signalling mechanisms and potential rescue strategies. Cardiovascular Research, 115(5), 966–977.

Umbarkar, P., Tousif, S., Singh, A. P., Anderson, J. C., Zhang, Q., Tallquist, M. D., et al. (2022). Fibroblast GSK-3α promotes fibrosis via RAF-MEK-ERK pathway in the injured heart. Circulation Research, 131(7), 620–636.

Singh, A. P., Umbarkar, P., Tousif, S., & Lal, H. (2020). Cardiotoxicity of the BCR-ABL1 tyrosine kinase inhibitors: Emphasis on ponatinib. International Journal of Cardiology, 316, 214–221.

Umbarkar, P., Singh, A. P., Gupte, M., Verma, V. K., Galindo, C. L., Guo, Y., Zhang, Q., et al. (2019). Cardiomyocyte SMAD4-dependent TGF-β signaling is essential to maintain adult heart homeostasis. JACC: Basic to Translational Science, 4(1), 41–53.

Tousif, S., Singh, A. P., Umbarkar, P., Galindo, C., Wheeler, N., Toro Cora, A., et al. (2023). Ponatinib drives cardiotoxicity by S100A8/A9-NLRP3-IL-1β mediated inflammation. Circulation Research, 132(3), 267–289.