Darya Novopashina | Genetics and Molecular Biology | Research Excellence Award

Published on by Citation Awards

Darya Novopashina | Genetics and Molecular Biology | Research Excellence Award

Institute of Chemical Biology and Fundamental Medicine SB RAS | Russia

Dr. Darya Novopashina, Ph.D., is a senior researcher at the Laboratory of RNA Chemistry, Institute of Chemical Biology and Fundamental Medicine, SB RAS, where she has built a distinguished career in nucleic acid chemistry and bioorganic research. Her scientific work spans the design, synthesis, and functional exploration of modified oligoribonucleotides, with early contributions focused on creating conjugates of chemically altered RNA fragments for targeted gene expression inhibition. Over the years, she has advanced this foundation by investigating hybrid structures formed between nucleic acid fragments and carbon nanotubes, offering new insights into nanobiotechnology and molecular detection technologies. She has also developed innovative fluorescent oligonucleotide probes aimed at improving the sensitivity and specificity of nucleic acid detection methods. Currently, her research centers on engineering modified guide RNAs for CRISPR/Cas9 systems, where she has contributed to the development of light- and small-molecule–regulatable genome-editing platforms that enhance precision, control, and versatility in genetic manipulation. Through her work, Dr. Novopashina has become a key contributor to the evolution of RNA-based tools in molecular biology, enabling improvements in gene regulation, diagnostic capabilities, and therapeutic strategies. With a publication record exceeding 60 scientific papers, she is recognized for her consistent contributions to the fields of chemical biology, RNA modification, and genome-engineering technologies.

Profile: Orcid | Scopus

Featured Publications

Gavrilova, A. A., Kuznetsova, A. A., Novopashina, D. S., Zheng, C., Sun, Q., & Kuznetsov, N. A. (2025).
Biochemical characterization of R-loop degradation by chloroplast-localized RNase H1 from Arabidopsis thaliana. International Journal of Molecular Sciences, 26(22),

Kamzeeva, P., Shepelev, N., Zabbarova, V., Brylev, V., Chistov, A., Ryazantsev, D., Kot, E., Novopashina, D., Rubtsova, M., & Aralov, A. (2025).
Structural characterization of DDX23 5′ UTR regulatory elements and their targeting by LNA-modified antisense oligonucleotides. International Journal of Molecular Sciences, 26(22),

Dolzhikova, O., Meschaninova, M., Endutkin, A., Golyshev, V., Vorobyeva, M., & Novopashina, D. (2024).
Design of theophylline binding guide RNA for allosteric regulation of CRISPR/Cas9 system [Preprint]. Preprints.

Sakovina, L., Vokhtantsev, I., Akhmetova, E., Vorobyeva, M., Vorobjev, P., Zharkov, D. O., & Novopashina, D. (2024).
Photocleavable guide crRNAs for a light-controllable CRISPR/Cas9 system. International Journal of Molecular Sciences, 25(22),

 Kuznetsova, A. A., Kosarev, I. A., Timofeyeva, N. A., Novopashina, D. S., & Kuznetsov, N. A. (2024).
Kinetic features of degradation of R-loops by RNase H1 from Escherichia coli. International Journal of Molecular Sciences, 25(22),

Siva Vijayakumar Tharumasivam | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Published on by Citation Awards

Siva Vijayakumar Tharumasivam | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Dr.Siva Vijayakumar Tharumasivam, Dhanalakshmi Srinivasan University, India

Dr. T. Siva Vijayakumar (M.Sc., Ph.D., D.Sc. Honoris Causa) is a dedicated academician and accomplished researcher in Biotechnology, currently serving as Associate Dean – HRDC at Dhanalakshmi Srinivasan University, Tamil Nadu. With a dual role as Flying Officer in the Indian NCC (Airwing), his career embodies leadership in both academia and service. Dr. Vijayakumar’s dynamic research covers aquatic toxicology, nanobiotechnology, neurodegenerative diseases, and regenerative medicine. He has guided numerous students in pioneering scientific exploration and has authored over 48 publications in reputed journals. A passionate mentor, he integrates innovative methodologies in research and education, ensuring his students gain holistic scientific exposure. His expertise has earned national recognition, contributing to scientific knowledge and societal progress. Committed to sustainable solutions, his work addresses pressing environmental and health challenges through nanoscience and biotechnology. His impactful contributions continue to inspire emerging scientists and institutions alike. 🌿🔬🇮🇳

Publication Profile

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Education

Dr. Siva Vijayakumar pursued his Master of Science (M.Sc.) in Biotechnology, followed by a Doctor of Philosophy (Ph.D.), with an academic journey grounded in molecular biology, toxicology, and applied nanoscience. Recognized for his significant contributions to the field, he was conferred with a Doctor of Science (D.Sc.) Honoris Causa by the International Agency for Standards and Rating in 2021. His education reflects a strong emphasis on multidisciplinary integration, blending core biological sciences with technological innovations. He has continually upgraded his scientific expertise through hands-on research, workshops, and training programs. His educational foundation has enabled him to bridge theoretical knowledge with practical applications in fields such as drug delivery, aquatic environmental health, and regenerative biology. Through his academic pursuits, he has mentored future scientists, instilling a rigorous yet innovative approach to biotechnology. 📘🧬🎓

Experience

Dr. Vijayakumar has over a decade of teaching and research experience in biotechnology. Currently, he holds the position of Associate Dean – Human Resource Development Centre (HRDC) at the Department of Biotechnology, Dhanalakshmi Srinivasan University, Tamil Nadu. He also serves as a Flying Officer and Associate NCC Officer (3TN Air Squadron NCC, Trichy), promoting discipline and patriotism among students. His academic leadership spans curriculum development, research mentoring, and interdisciplinary program coordination. He has played a pivotal role in conducting national workshops, guiding research scholars, and collaborating on funded projects. His administrative experience has fortified institutional growth through strategic planning and research integration. As a faculty member and leader, he’s known for fusing technology with biological sciences, emphasizing innovation, and cultivating global scientific perspectives among students. 🧪📚✈️

Awards and Honors

Dr. Siva Vijayakumar has been honored with several prestigious awards recognizing his excellence in research and education. Notable among them is the Guru Samman Award 2025 🧑‍🏫 by AISPCPA, Bengaluru, and the Innovative Research Award 2023 🧠 by Rover Agricultural College, Perambalur. In 2021, he received the Honorary Doctorate in Biotechnology (D.Sc.) 🎓 and the Research Excellence Award 🏆 by the Institute of Scholars. His early research acumen earned him the Young Investigator Award 2020 🔍 from DERO and the Best Young Scientist Award 2017 🧬 by PEARL Foundation. These accolades reflect his dedication to advancing biotechnology, inspiring students, and contributing meaningfully to scientific society. His recognition across both academic and service domains illustrates a career committed to innovation, leadership, and impact. 🌟🏅

Research Focus

Dr. Vijayakumar’s primary research revolves around Aquatic Toxicology and Nanobiotechnology, emphasizing the impact of engineered nanomaterials (ENMs) on aquatic ecosystems. He investigates the toxicity, transport, bioaccumulation, and ecological impact of nanoparticles, including their genotoxic and ecotoxic consequences. His research extends to drug delivery systems, exploring biocompatibility, host responses, and novel therapeutics for neurodegenerative diseases and tissue regeneration. His interdisciplinary approach bridges molecular biology, environmental science, and materials engineering. A strong advocate for eco-safe nanotechnology, he integrates in vitro, in vivo, and computational models to assess risk and functionality. His team engages in animal model studies, molecular simulations, and regenerative biomaterial design, contributing to innovations in environmental health and biomedical applications. His vision is to foster sustainable and safe biotechnological advancements for future healthcare and environmental well-being. 🌊🧪🧠

Publication Top Notes

  1. 🧬 Exploring Piperine as a Potential Treatment for Polycystic Ovarian Syndrome: Insights from In-silico Docking Studies (2024)

  2. 🐟 Toxicity Assessment on Haematology and Enzymological Alterations of Al₂O₃ Nanoparticles Exposed Freshwater Fish (2024)

  3. 🌿 Exploring Potential Anti-aging Compounds and Binding Affinity of Resveratrol with hTERT Gene (2024)

  4. 🧠 Computational Analysis of Anti-Alzheimer’s Efficacy of Myristicin from Nutmeg (2024)

  5. 🧫 Characterization of Novel Antimicrobial Peptides from Clarias Batrachus (2024)

  6. 💧 Carbon Nanoparticles Fabricated Microfilm for Microplastics Filtration (2023)

  7. 🩹 Functional 2D Graphene Oxide in the Wound Healing Process (2023)

  8. 🦐 Probiotics-Infused Withania Somnifera for Shrimp Development (2023)

  9. 🧪 Fabrication of Silver Nanoparticles using Illicium Verum and Its Anti-bacterial Activity (2023)

  10. 🍇 Pharmacological Properties and Mode of Action of Quercetin: A Bioactive Flavonoid (2023)

  11. 🌱 Anti-inflammatory Activity of Ocimum Tenuiflorum-loaded Chitosan Nanoparticles (2023)

  12. 🧬 Complete Overview of Enzymatic Responses in Nanoparticle-Stressed Fish Models (upcoming)