Anna Lankoff | Genetics and Molecular Biology | Best Researcher Award

Anna Lankoff | Genetics and Molecular Biology | Best Researcher Award

Prof Anna Lankoff, Institute of Nuclear Chemistry and Technology, Centre for Radiobiology and Biological Dosimetry, Poland

Prof. Anna Lankoff is a distinguished scientist and educator renowned for her contributions to genotoxicology, nanotoxicology, and radiobiology. πŸ‘©β€πŸ”¬πŸ§ͺ With over three decades of experience, she has made groundbreaking advancements in the study of ionizing radiation-induced DNA damage, nanoparticle-based radioconjugates for cancer therapy, and cellular responses to nanomaterials. πŸŒπŸ”¬ Currently, she holds full professorships at both the Institute of Nuclear Chemistry and Technology in Warsaw and Jan Kochanowski University in Kielce, where she leads the Cytogenetics and Genotoxicology Laboratories. πŸ’‘πŸ“˜ Her collaborative work spans across institutions in Germany, Finland, Belgium, and the USA. She is a respected academic leader, actively participating in global expert committees including WHO-IARC and the European Radiation Research Council. πŸŒπŸ“š With 85 peer-reviewed papers, 3797 citations, and an h-index of 30, Prof. Lankoff exemplifies excellence in research and education, making her an ideal candidate for the Best Researcher Award. πŸ†πŸ”

Publication Profile

Orcid

EducationΒ 

Prof. Anna Lankoff began her academic journey with an MSc in Biology (1986–1991) from Jan Kochanowski University, Kielce, Poland. πŸŽ“πŸ”¬ She earned her PhD in Toxicology in 1999 from Maria Sklodowska-Curie University in Lublin, Poland. πŸ’ŠπŸ“˜ Her research prowess led her to complete a prestigious postdoctoral fellowship in 2003 at Wright State University in Dayton, Ohio, USA, in the Department of Biological Sciences. 🌍🧬 In 2007, she achieved her DSc (habilitation) in Biological Sciences from the Institute of Biochemistry and Biophysics of the Polish Academy of Sciences. πŸ§«πŸ“– By 2014, she was awarded the title of Full Professor in Biological Sciences, marking a significant milestone in her academic career. 🌟 Her extensive academic preparation laid the foundation for a prolific scientific and educational path in radiobiology, cytogenetics, and nanotoxicology. πŸ§ πŸ’Ό

ExperienceΒ 

Prof. Lankoff has an extensive academic and research career. Since 2014, she has been a Full Professor at both the Institute of Nuclear Chemistry and Technology, Warsaw, and Jan Kochanowski University, Kielce. πŸ§ͺπŸ‡΅πŸ‡± She leads laboratories in cytogenetics and genotoxicology. From 2009–2014, she served as Associate Professor at these institutions, and previously, as a lecturer and assistant since 1991. πŸ“˜πŸ‘©β€πŸ« Her international experience includes research stints at University of Duisburg-Essen (Germany), Wright State University (USA), VITO (Belgium), and Γ…bo Akademi University (Finland). πŸŒπŸ” She has mentored numerous students and professionals in molecular biology, immunology, and nanotoxicology. Her professional journey reflects dedication to excellence in both teaching and cutting-edge scientific research. πŸ’‘πŸ§¬

Awards and HonorsΒ 

Prof. Anna Lankoff’s contributions have been recognized internationally. 🌟 She was a working group member for the WHO-IARC (2006) and an expert for the EU’s β€œEpigenetic effects” radiation protection group (2017). πŸŒπŸ”¬ She represented Poland on the ISO Radiology Standards Committee (2010–2015) and serves on the Scientific Council of the Institute of Nuclear Chemistry and Technology and the Polish Society for Radiation Research. πŸ‡΅πŸ‡±πŸ“˜ She is also a member of the European Radiation Research Council since 2022. πŸ§ͺπŸ’‘ Her work has earned her recognition for developing standards in biological dosimetry and contributions to nanotoxicology and radiation biology. πŸ“œπŸ” With a prolific academic record of 85 JCR-listed publications and over 3,700 citations, she holds an h-index of 30. πŸ“š Her impactful global collaborations, editorial work, and advisory roles highlight her as a true leader in radiobiological research and innovation. πŸ§¬πŸ†

Research FocusΒ 

Prof. Lankoff’s research integrates nanotechnology, radiobiology, and molecular biology. 🧬 Her focus areas include the genotoxicity and cytotoxicity of nanomaterials, development of nanoparticle-based radioconjugates for targeted cancer diagnosis and therapy, and the mechanisms of DNA damage and repair induced by ionizing radiation. πŸ’₯πŸ§ͺ She investigates cellular responses such as cell cycle arrest, apoptosis, and pyroptosis in reaction to nanomaterial exposure and radiation treatment. 🧫 Her recent work explores nanotheranostics, blackcurrant-derived antioxidants, and radiosensitization strategies using natural compounds. πŸŒΏπŸ’‰ She also delves into biodistribution, pharmacokinetics of engineered nanostructures, and radiobiological safety, bridging basic science with translational medicine. 🌐🧠 Prof. Lankoff’s innovative research contributes to the development of safer nanomaterials and more effective cancer therapies, reinforcing her status as a pioneering researcher in modern molecular and radiation biology. πŸ§ͺπŸ”¬πŸ“ˆ

Publication Top Notes

  1. πŸ“˜ Advances in Nanotheranostic Systems for Concurrent Cancer Imaging and Therapy: An Overview of the Last 5 Years (2024)

  2. πŸ§ͺ Nanoparticle-Based Radioconjugates for Targeted Imaging and Therapy of Prostate Cancer (2023)

  3. ☒️ Hypothermia Modulates NBS1, γH2AX and 53BP1 Foci in U2OS Cells Post Gamma Radiation (2022)

  4. πŸ‡ Blackcurrant Pomace Protects Rats from Testicular Oxidative Stress from Biodiesel Exhaust (2022)

  5. πŸ”¬ Surface Modification of Gold Nanoparticles Triggers Pyroptosis-Inducing Cytokine Release (2022)

  6. πŸ’‰ Targeted NaA Nanozeolites for Prostate Cancer Therapy: Toxicity and Pharmacokinetics (2021)

  7. 🧬 Cisplatin Lowers Radiotherapy-Induced Micronuclei in Lymphocytes of Gynaecological Cancer Patients (2021)

  8. πŸ“ˆ Coralyne Radiosensitizes A549 Cells by CDKN1A Upregulation Affecting G2/M Cell Cycle Arrest (2021)

 

Santina Bruzzone | Genetics and Molecular Biology | Best Researchers Award

Santina Bruzzone | Genetics and Molecular Biology | Best Researchers Award

Santina Bruzzone,UniversitΓ  di Genova,Italy

Santina Bruzzone is a Full Professor of Biochemistry at the University of Genova, Italy. She was born on February 21, 1972, in Genova, Italy. Her research focuses on the role of NAD+ and NAD+-converting enzymes in inflammation and cancer.

Publication Profile

Scopus

Education

Santina Bruzzone completed her high school education at Liceo Scientifico L. Lanfranconi in Genova, Italy, from 1986 to 1991. She then earned her degree in Biology from the University of Genova, graduating cum laude with a score of 110/110 in 1996. She received her Ph.D. in Biotechnology applied to Pharmacology and Cellular and Molecular Biotechnology applied to Biomedicine from the University of Milano from 1996 to 2000.

Experince

Santina Bruzzone worked as a postdoctoral researcher at the Department of Experimental Medicine (DIMES)–Section of Biochemistry, University of Genova, from January to March 2001. She then worked as a postdoctoral researcher at the Department of Pharmacology, University of Minnesota, from April to December 2001. She returned to the University of Genova as a postdoctoral researcher from 2002 to 2005 and later became an Assistant Professor of Biochemistry from 2005 to 2016. She was promoted to Associate Professor of Biochemistry from 2016 to 2021 and became a Full Professor of Biochemistry in 2021.

Award and Honors

Santina Bruzzone received several awards and honors, including the Fellowship for training abroad from Consorzio Interuniversitario Biotecnologie (CIB) in 2001, the Fellowship for training abroad from the University of Genova in 2001, and the Faculty Research Visit Grant from DAAD (German Academic Exchange Service) in 2013.

Research Focus

Santina Bruzzone’s research focuses on the role of NAD+ and NAD+-converting enzymes in inflammation and cancer. Her work explores the molecular mechanisms underlying the regulation of NAD+ metabolism and its impact on cellular processes such as energy metabolism, cell signaling, and cell death.

Publications

1. 🌟 CD38 and ADP-ribosyl cyclase catalyze the synthesis of a dimeric ADP-ribose that potentiates the Calcium-mobilizing activity of Cyclic ADP-ribose. (1997)
2. 🌟 Ectocellular CD38-catalyzed synthesis and intracellular Ca2+-mobilizing activity of Cyclic ADP-ribose. (1998)
3. 🌟 Expression of CD38 increases intracellular calcium concentration and reduces doubling time in HeLa and 3T3 cells. (1998)
4. 🌟 The transmembrane glycoprotein CD38 is a catalytically active transporter responsible for generation and influx of the second messenger Cyclic ADPribose across membranes. (1998)
5. 🌟 Dimeric and tetrameric forms of catalytically active transmembrane CD38 in transfected HeLa cells. (1998)
6. 🌟 Ligand-induced internalization of CD38 results in intracellular Ca2+ mobilization. (1999)
7. 🌟 Topology of CD38. (2000)
8. 🌟 Extracellular cyclic ADP-ribose increases intracellular free calcium concentration and stimulates proliferation of human hemopoietic progenitors. (2000)
9. 🌟 G(s) protein dysfunction in allergen-challenged human isolated passively sensitized bronchi. (2000)
10. 🌟 Connexin 43 hemichannels mediate Ca2+-regulated transmembrane NAD+ fluxes in intact cells. (2001)
11. 🌟 Extracellular Cyclic ADP-ribose potentiates Ach-induced contraction in bovine tracheal smooth muscle. (2001)
12. 🌟 Human CD38 and its ligand CD31 define a unique lamina propria T lymphocyte signaling pathway. (2001)
13. 🌟 Paracrinally stimulated expansion of early human hemopoietic progenitors by stroma-generated cyclic ADP-ribose. (2001)
14. 🌟 Paracrine roles of NAD+ and Cyclic ADP-ribose in increasing intracellular calcium and enhancing cell proliferation of 3T3 fibroblasts. (2001)
15. 🌟 Autocrine abscisic acid mediates the UV-B-induced inflammatory response in human granulocytes and keratinocytes. (2012)
16. 🌟 ABA says NO to UV-B: a universal