Ashish Kumar Singhi | Biological Sciences | Best Researcher Award

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Dr. Ashish Kumar Singhi | Biological Sciences | Best Researcher Award

Scientist at ICAR-Vivekananda Parvatiya Krishi Anusandhan Sansthan, Almora, India

Dr. Ashish Kumar Singh is a distinguished professional in the field of nematology and agricultural research, renowned for his expertise and contributions. With a solid educational foundation including a Ph.D. in Nematology from ICAR – Indian Agricultural Research Institute, New Delhi, he has garnered extensive experience and recognition in his field. Throughout his career, Dr. Singh has excelled in nematode biodiversity assessment, management under protected cultivation, and insect pest management. His research spans critical areas such as entomopathogenic nematodes, bacterial genomics, and the impact of fertilization on soil nematodes, emphasizing sustainable agricultural practices and soil health management.

Professional Profiles:

📚 Education:

Dr. Ashish Kumar Singh has an extensive educational background in agricultural sciences with a strong focus on nematology. He graduated with a B.Sc. in Agriculture from UPAC, Varanasi, India, from 2008 to 2012. Following this, he pursued an M.Sc. in Nematology at ICAR-IARI, New Delhi, India, from 2013 to 2015, specializing in plant pathology, plant biotechnology, and nematology. Dr. Singh further advanced his expertise by earning a Doctorate (Ph.D.) in Nematology from ICAR-IARI, New Delhi, India, between 2015 and 2021. During his doctoral studies, he worked on significant research projects including the evaluation of root knot nematode responsive promoters against important plant parasitic nematodes, and the draft genome of the seed gall nematode (Anguina tritici, Steinbuch, 1799). Dr. Singh possesses a diverse skill set encompassing nematology, plant pathology, molecular biology, biotechnology, and bioinformatics. His research and academic pursuits highlight his commitment to advancing agricultural sciences and addressing critical issues in plant health and nematode management. With practical experience in agriculture and rural settings, Dr. Singh’s work contributes significantly to the understanding and management of plant parasitic nematodes. You can follow his professional updates and research activities on Twitter at @ashishnematode.

Professional Experience:

Dr. Ashish Kumar Singh has garnered substantial professional experience in various facets of agricultural research and nematode management. Since July 2022, he has been working as a Scientist (Senior Scale) at ICAR-Vivekananda Parvatiya Krishi Anusandhan Sansthan, Almora. In this role, Dr. Singh focuses on nematode biodiversity assessment, nematode management under protected cultivation, insect pest management, and entomopathogenic nematodes. He also delves into bacterial genomics, white grub gut bacterial metagenomics, and the long-term impact of fertilization on soil nematodes, examining nematodes as indicators of soil health. Before his current position, from July 2018 to July 2022, Dr. Singh served as a Scientist at the same institution. His contributions during this period were crucial in advancing the understanding and management of nematodes and other related agricultural issues. In July 2018, Dr. Singh attended the 108th Foundation Course for Agricultural Research Service (FOCARS) at the ICAR-National Academy of Agricultural Research Management, Hyderabad. This three-month training program was designed to enhance the competencies of research management through various components and modules, equipping Dr. Singh with essential skills and knowledge for his scientific career. Dr. Singh’s professional journey reflects his dedication to improving agricultural practices and managing nematode-related challenges. His expertise and research continue to play a significant role in the field of agricultural science, particularly in the areas of nematode management and soil health.

Awards and Honors:

Dr. Ashish Kumar Singh has received numerous awards and honors throughout his academic and professional career, reflecting his significant contributions to the field of nematology and agricultural research. In February 2022, he was honored with the “Best Oral Presentation” award by the Phytopathological Society of India, New Delhi. This recognition was for presenting a research paper at the National Symposium on “Recent Trends in Phytopathology to Address Emerging Challenges for Achieving Food Security.” His outstanding presentation highlighted his research’s relevance and impact in addressing phytopathological challenges. Dr. Singh also won the “First Prize” from the State Department of Uttarakhand for an institute tableau display on Republic Day, showcasing his commitment to community engagement and public education. In March 2022, he was recognized as the “Best Trainee” at a capacity-building workshop in Nematode taxonomy and a satellite symposium on Advances in Nematology, hosted by the Department of Zoology, CCS University, Meerut, in collaboration with DRDO. This award underscored his expertise and excellence in the specialized field of nematode taxonomy. His academic journey was marked by securing a “Junior Research Fellowship” from the Indian Council of Agricultural Research (ICAR), New Delhi, for pursuing an M.Sc. in Nematology from 2013 to 2015. He continued to excel by obtaining an “ICAR Senior Research Fellowship” from ICAR, New Delhi, for his Ph.D. studies in Nematology. Additionally, Dr. Singh was awarded the prestigious “IARI Meritorious Scholarship” from ICAR – Indian Agricultural Research Institute, New Delhi, for his Ph.D. studies. Dr. Singh successfully passed the “National Eligibility Test (NET)” conducted by the Agricultural Scientists Recruitment Board (ASRB), New Delhi, further establishing his qualifications and readiness for a career in agricultural research. His research excellence was also recognized with the “Best Research Presentation Award” by the Nematological Society of India.

 

📚Publications :

Unveiling the Draft Genome of the Seed Gall Nematode, Anguina tritici: Insights and Analysis

Journal: Physiological and Molecular Plant Pathology

Date: June 2024

DOI: 10.1016/j.pmpp.2024.102330

Citations: –

Authors: Ashish Kumar Singh

A Draft Transcriptome Announcement of Anguina tritici

Journal: Journal of Nematology

Date: March 2024

DOI: 10.2478/jofnem-2024-0007

Citations: –

Authors: Ashish Kumar Singh

Detection of Meloidogyne graminicola (RRKN) in Kumaon region of the Indian Himalayas

Journal: The Indian Journal of Agricultural Sciences

Date: August 2023

DOI: 10.56093/ijas.v93i7.135351

Citations: –

Authors: Ashish Kumar Singh

Unravelling geospatial distribution and genetic diversity of greenhouse whitefly, Trialeurodes vaporariorum (Westwood) from Himalayan Region

Journal: Scientific Reports

Date: July 2023

DOI: 10.1038/s41598-023-37781-y

Citations: –

Authors: Ashish Kumar Singh

Collective effect of host delivered RNAi splicing factor and integrase gene on the reproductive potential of root-knot nematode (Meloidogyne incognita)

Journal: The Pharma Innovation Journal

Date: May 2023

Citations: –

Authors: Ashish Kumar Singh

Nematode Genome Announcement: A Draft Genome of Seed Gall Nematode, Anguina tritici

Journal: Journal of Nematology

Date: February 2023

DOI: 10.2478/jofnem-2023-0031

Citations: –

Authors: Ashish Kumar Singh

Molecular characterization of necromenic nematode Pristionchus pacificus and associated bacteria: A new record

Journal: –

Date: October 2022

Citations: –

Authors: Ashish Kumar Singh

Chitosan and chitosan-based nanoparticles for eco-friendly management of plant diseases and insect pests: a concentric overview

Publication Type: Book Chapter

Book Title: Role of Chitosan and Chitosan-Based Nanomaterials in Plant Sciences

Date: 2022

DOI: 10.1016/b978-0-323-85391-0.00003-4

Citations: –

Authors: Ashish Kumar Singh

Understanding the Relationship Between Pesticide Residue and Rhizospheric Process in Soil Ecosystems

Journal: Climate Change and Environmental Sustainability

Date: 2022

Volume: 10, Issue 2

Pages: 123-131

Citations: –

Authors: Ashish Kumar Singh

Role of Plant-Associated Microbes in Phytoremediation of Heavy Metal Polluted Soils

Publication Type: Book Chapter

Book Title: Heavy Metal Toxicity in Plants

Date: November 2021

DOI: 10.1201/9781003155089-12

Citations: –

Authors: Ashish Kumar Singh

Conferring root-knot nematode resistance via host-delivered RNAi-mediated silencing of four Mi-msp genes in Arabidopsis

Journal: Plant Science

Date: 2020

DOI: 10.1016/j.plantsci.2020.110592

EID: 2-s2.0-85087791294

Citations: –

Authors: Ashish Kumar Singh

 

Jingyi Jin | Pharmacology | Best Researcher Award

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Mrs. Jingyi Jin | Pharmacology | Best Researcher Award

 

Research Assistant at Shuguang hospital affiliated to Shanghai University of Traditional Chinese Medicine, China

Mrs. Jingyi Jin is an accomplished researcher in the field of pharmacokinetics, with a strong academic background and extensive practical experience. She is currently pursuing her Master’s degree in Pharmacokinetics at the Shanghai University of Traditional Chinese Medicine, having previously earned a Master’s degree in the same field from Paris Descartes University. Her academic journey began with a Bachelor’s degree in Traditional Chinese Medicine from the Shanghai University of Traditional Chinese Medicine, where she graduated in the top 3% of her class. Mrs. Jin’s research has focused on the pharmacokinetics of traditional Chinese medicinal compounds, with notable projects including the study of Da-Huang-Xiao-Shi Decoction in mice, the transport mechanisms of venlafaxine and its metabolite in hCMEC/D3 cells, and the involvement of transport proteins in the efflux of berberine. Her work has provided valuable insights into drug interactions, bioavailability, and the optimization of combination therapies. In addition to her research, Mrs. Jin has developed a comprehensive skill set in experimental techniques, including animal handling, cell culture, transfection technology, and advanced analytical methods using mass spectrometry and liquid chromatography. Her dedication, responsibility, and logical thinking have been recognized through multiple awards and scholarships, underscoring her excellence as a student and researcher. Overall, Mrs. Jingyi Jin’s expertise in pharmacokinetics, combined with her practical skills and academic achievements, make her a significant contributor to the field of Traditional Chinese Medicine and modern pharmacology. Her work continues to advance our understanding of medicinal compounds and their therapeutic applications.

Professional Profiles:

📚 Education:

Mrs. Jingyi Jin has a strong academic background in the field of pharmacokinetics and Traditional Chinese Medicine. She is currently pursuing her Master’s degree in Pharmacokinetics at the Shanghai University of Traditional Chinese Medicine, where she has been studying since 2015. During this time, she has focused on the pharmacokinetics of traditional Chinese medicinal compounds, contributing to the advancement of this specialized field. In addition to her studies in China, Mrs. Jin furthered her expertise by obtaining a second Master’s degree in Pharmacokinetics from Paris Descartes University in 2018. This international experience provided her with a broader perspective and deeper understanding of pharmacokinetics, particularly in the context of Western and Chinese medicinal practices. Prior to her master’s studies, Mrs. Jin completed her Bachelor’s degree in Traditional Chinese Medicine at the Shanghai University of Traditional Chinese Medicine in 2015, graduating in the top 3% of her class. Her undergraduate education laid a solid foundation in both the theoretical and practical aspects of Traditional Chinese Medicine, which she has built upon through her advanced research and studies. This rigorous academic journey has equipped Mrs. Jin with the knowledge and skills necessary to excel in her field and contribute meaningfully to scientific research and development.

Research Interests:

Mrs. Jingyi Jin has made significant contributions to the field of pharmacokinetics through her extensive research endeavors. Since May 2018, she has been investigating the pharmacokinetics of Da-Huang-Xiao-Shi Decoction in mice, focusing on understanding the absorption, distribution, metabolism, and excretion of this traditional Chinese medicinal formulation. Her work aims to elucidate the pharmacological basis of its therapeutic effects and optimize its clinical use. From May 2017 to April 2018, Mrs. Jin studied the transport mechanisms of venlafaxine and its main metabolite, O-desmethylvenlafaxine, in hCMEC/D3 cells. This research was pivotal in understanding how these compounds cross the blood-brain barrier, providing insights into their efficacy and safety as antidepressants. Prior to this, she examined the involvement of P-glycoprotein and multidrug and toxin extrusion protein 1 in the hepatic and renal efflux of berberine in mice from September 2015 to April 2017. This study highlighted the roles of these transport proteins in drug-drug interactions and their impact on berberine’s bioavailability and therapeutic effectiveness. Mrs. Jin’s early research, conducted from December 2014 to August 2015, focused on the absorption interaction between berberine and metformin in vitro. This study explored the synergistic effects of these two compounds, commonly used in the treatment of type 2 diabetes, and provided a foundation for optimizing combination therapies. Through these diverse research projects, Mrs. Jin has demonstrated a robust ability to conduct detailed pharmacokinetic studies, contributing valuable knowledge to the field and enhancing the scientific understanding of traditional Chinese medicines and modern pharmaceuticals.

Skills:

Mrs. Jingyi Jin possesses a comprehensive set of experimental skills, honed through years of rigorous academic training and hands-on research experience. She is proficient in the routine operation of mice and rats, which includes handling, dosing, and sample collection. Her expertise in animal studies is complemented by her proficiency in cell culture techniques, where she excels in the cultivation and maintenance of various cell lines. Mrs. Jin is also skilled in transfection technology, enabling her to introduce foreign DNA into cells to study gene function and expression. In addition to these foundational skills, Mrs. Jin has mastered several advanced analytical techniques. She is experienced in conducting transport assays, which are critical for understanding the movement of substances across cell membranes. Her technical repertoire includes the use of sophisticated instruments such as the Thermo Scientific TSQ and LCQ mass spectrometers, and she is familiar with Ultra-Performance Liquid Chromatography (UPLC) and the 5500 QTRAP system. These skills are crucial for the establishment and validation of analytical methods used in pharmacokinetic studies. Mrs. Jin’s ability to integrate these diverse experimental techniques demonstrates her versatility and depth of knowledge in pharmacokinetics and drug metabolism. Her proficiency with both in vivo and in vitro models positions her as a valuable asset in the field of pharmacokinetics research, contributing to the advancement of our understanding of drug interactions and mechanisms.

 

📚Publications :

Gancao decoction attenuates hepatic necroptosis via activating caspase 8 in cholestatic liver injury

Authors: Zou, B., Zhang, S., Li, F., …, Li, Y., Qiu, F.

Journal: Journal of Ethnopharmacology

Year: 2024

Citations: 1

Simultaneous determination of 11 oral targeted antineoplastic drugs and 2 active metabolites by LC-MS/MS in human plasma and its application to therapeutic drug monitoring in cancer patients

Authors: Zhao, J., Yan, D., Li, Y., …, Jin, J., Qiu, F.

Journal: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Year: 2024

Citations: 0

Physiologically based pharmacokinetic modeling for confirming the role of CYP3A1/2 and P-glycoprotein in detoxification mechanism between glycyrrhizic acid and aconitine in rats

Authors: Jin, J., Xu, X., Li, F., …, Yan, D., Qiu, F.

Journal: Journal of Applied Toxicology

Year: 2024

Citations: 0

Glycyrrhetinic acid attenuates endoplasmic reticulum stress-induced hepatocyte apoptosis via CHOP/DR5/Caspase 8 pathway in cholestasis

Authors: Zou, B., Zhang, S., Zhao, J., …, Li, Y., Qiu, F.

Journal: European Journal of Pharmacology

Year: 2023

Citations: 2

Yinchen decoction protects against cholic acid diet-induced cholestatic liver injury in mice through liver and ileal FXR signaling

Authors: Song, G., Zou, B., Zhao, J., …, Liu, C., Qiu, F.

Journal: Journal of Ethnopharmacology

Year: 2023

Citations: 3

The choleretic role of tauroursodeoxycholic acid exacerbates alpha-naphthylisothiocyanate induced cholestatic liver injury through the FXR/BSEP pathway

Authors: Zhao, J., Song, G., Weng, F., …, Liu, C., Qiu, F.-R.

Journal: Journal of Applied Toxicology

Year: 2023

Citations: 1

Potential therapeutic action of tauroursodeoxycholic acid against cholestatic liver injury via hepatic Fxr/Nrf2 and CHOP-DR5-caspase-8 pathway

Authors: Song, G., Weng, F., Zou, B., …, Li, Y., Qiu, F.

Journal: Clinical Science

Year: 2023

Citations: 5

15,16-dihydrotanshinone I in Danshen ethanol extract aggravated cholestasis by inhibiting Cyp3a11 mediated bile acids hydroxylation

Authors: Li, Y., Wang, Q., Jin, J., …, Yan, D., Qiu, F.

Journal: Toxicology Letters

Year: 2023

Citations: 1

Application progress of liquid chromatography tandem mass spectrometry in precision medicine

Authors: Jin, J., Qiu, F., Zhang, J.

Journal: Chinese Journal of Preventive Medicine

Year: 2022

Citations: 0

Hepatoprotective Effects of Glycyrrhetinic Acid on Lithocholic Acid-Induced Cholestatic Liver Injury Through Choleretic and Anti-Inflammatory Mechanisms

Authors: Wang, Q., Song, G.-C., Weng, F.-Y., …, Li, Y., Qiu, F.-R.

Journal: Frontiers in Pharmacology

Year: 2022

Citations: 11